A Bioinspired, One-Step Total Synthesis of Peshawaraquinone. de Castro, T.; Huang, D.; Sumby, C.; Lawrence, A. L.; George J.* Chem. Sci. 2023, 14, 950–954.
Total Synthesis and Prediction of Ulodione Natural Products Guided by DFT Calculations. Bestwick, J. S.; Jones, D. J.; Jones, H. E.; Kalomenopoulos, P. G.; Szabla, R.;* Lawrence, A. L.* Angew. Chem. Int. Ed. 2022, e202207004.
Natural Product Anticipation Through Synthesis. Hetzler, B. E.; Trauner, D.;* Lawrence, A. L.* Nat. Rev. Chem. 2022, 6, 170–181.
Unified Total Synthesis of the Brevianamide Alkaloids Enabled by Chemical Investigations into their Biosynthesis. Godfrey, R. C.; Jones, H. E.; Green, N. J.; Lawrence, A. L.* Chem. Sci. 2022, 13, 1313–1322.
N-Phenylputrescine (NPP): A Natural Product Inspired Amine Donor for Biocatalysis. McKenna, C.; Štiblariková, M.; De Silvestro, I.; Campopiano, D. J.;* Lawrence, A. L.* Green Chem. 2022, 24, 2010–2016.
Enantioselective para-Claisen Rearrangement for the Synthesis of Illicium-Derived Prenylated Phenylpropanoids. Homer, J. A.; De Silvestro, I.; Matheson, E. J.; Stuart, J. T.; Lawrence, A. L.* Org. Lett. 2021, 23, 3248–3252.
HIGHLIGHTED ON THE ORGANIC CHEMISTRY PORTAL: Metal-Mediated C-C Ring Construction: The Lawrence Synthesis of Illicinone A D. F. Taber, Org. Chem. Highlights 2021, December 13.
Total Synthesis of Brevianamide A. Godfrey, R. C.; Green, N. J.; Nichol, G. S.; Lawrence, A. L.* Nat. Chem. 2020, 12, 615–619.
BEHIND THE PAPER BLOG: TOTAL Synthesis of BREVIANAMIDE A. GODFREY, R. C. NATURE RESEARCH CHEMISTRY COMMUNITY 2020 APRIL.
HIGHLIGHTED BY SYNTHESIS WORKSHOP VIDEOS: BREVIANAMIDE A SYNTHESIS WITH DR. BLANE ZAVESKY. 2020 JUNE.
HIGHLIGHTED BY THE Organic CHEMISTRY ResEARCH WEBSITE: BIOINSPIRED TOTAL SYNTHESIS OF BREVIANAMIDE. SCHEEFF, S. 2020 JUNE.
HIGHLIGHTED BY SYNFORM: TOTAL SYNTHESIS OF BREVIANAMIDE A. Synform, 2020, 11, A160–A162.
Total Synthesis of Incargranine A. Brown, P. D.; Lawrence, A. L.* Org. Biomol. Chem. 2019, 17, 1698–1702.
Highlighted in SYNFACTS: Synthesis of (±)-Incargranine A. Carreira, E. M. Synfacts 2018, 14, 671.
Hot Paper: Highlighted by the reviewers as being particularly interesting/significant research.
Invited contribution: 2019 New Talent collection
Bio-Inspired Domino oxa-Michael/Diels–Alder/oxa-Michael Dimerization of para-Quinols. Green, N. J.; Connolly, C. A.; Rietdijk, K. P. W.; Nichol, G. S.; Duarte, F.;* Lawrence, A. L.* Angew. Chem. Int. Ed. 2018, 57, 6198–6202.
Highlighted in ChemistryViews: New Route to Complex Polycyclic Molecules Noteworthy 2018 04 June.
High Activity and Efficient Turnover by a Simple, Self-Assembled “Artificial Diels–Alderase”. Martí-Centelles, V.; Lawrence, A. L.; Lusby P. J.* J. Am. Chem. Soc. 2018, 140, 2862–2868.
Highlighted in SYNFACTS: Intermolecular [4+2] Cycloadditions Catalyzed by an Artificial Enzyme Like Capsule. List, B.; Li, Y. Synfacts 2018, 14, 536.
The Importance of Asking “How and Why?” in Natural Product Structure Elucidation. Brown, P. D.; Lawrence, A. L.* Nat. Prod. Rep. 2017, 34, 1193–1202.
Young Career Focus: Dr Andrew L. Lawrence (University of Edinburgh, UK). Lawrence, A. L.* SynForm 2017, A115–A117.
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Total Synthesis of a Dimeric Thymol Derivative Isolated from Arnica sachalinensis. De Silvestro, I.; Drew, S. L.; Nichol, G. S.; Duarte, F.;* Lawrence, A. L.* Angew. Chem. Int. Ed. 2017, 56, 6813–6817.
Chosen as a “Hot Paper” by the editorial team: Hot Papers
Total Synthesis of (−)-Angiopterlactone B. Thomson, M. I.; Nichol, G. S.; Lawrence, A. L.* Org. Lett. 2017, 19, 2199–2201.
One of the most read Org. Lett. articles: Most read articles
Book Review – Science of Synthesis: Applications of Domino Transformations in Organic Synthesis, Workbench Edition, 2 Vol. Green, N. J.; Lawrence, A. L.* Synthesis 2016, 48, 4594–4594.
Total Synthesis of Millingtonine. Brown, P. D.; Lawrence, A. L.* Angew. Chem. Int. Ed. 2016, 55, 8421–8425.
Highlighted in SYNFACTS: Synthesis of Millingtonine. Carreira, E. M; Sondermann, P. Synfacts 2016, 12, 883.
Unified Total Synthesis of the Natural Products Endiandric Acid A, Kingianic Acid E, and Kingianins A, D, and F. Drew, S. L.; Sherburn, M. S.;* Lawrence, A. L.* Chem. Sci. 2015, 6, 3886–3890.
Highlighted in SYNFACTS: Total Syntheses of Endiandric Acid A, Kingianic Acid E, and Kingianins A, D, and F. Carreira, E. M; Westphal, M. Synfacts 2015, 11, 794.
Total Synthesis of Ramonanins A-D. Harvey, R. S.; Mackay, E. G.; Roger, L.; Paddon-Row, M. N.;* Sherburn, M. S.;* Lawrence, A. L.* Angew. Chem. Int. Ed. 2015, 54, 1795–1798.
Highlights from the 49th EUCHEM Conference on Stereochemistry Bürgenstock, Switzerland, May 2014. Bernardes, G. J. L.;* Lawrence, A. L.* Chem. Commun. 2014, 50, 10752–10757.
Total Synthesis and Structural Revision of the Alkaloid Incargranine B. Brown, P. D.; Willis, A. C.; Sherburn, M. S.; Lawrence, A. L.* Angew. Chem. Int. Ed. 2013, 52, 13273–13275.
Total Synthesis of Kingianins A, D and F. Drew, S. L.; Sherburn, M. S.;* Lawrence, A. L.* Angew. Chem. Int. Ed. 2013, 52, 4221–4224.
Highlighted in CHEMISTRY WORLD: Kingianin A. Docherty, P. Totally Synthetic 2013, 01 May.
Highlighted in CHEMISTRY IN AUSTRALIA: A Positively Radical Synthesis.Chemistry in Australia 2013, July, 11.
Total Synthesis of Incarviditone and Incarvilleatone. Brown, P. D.; Willis, A. C.; Sherburn, M. S.; Lawrence, A. L.* Org. Lett. 2012, 14, 4537–4539.
Highlighted in SYNFACTS: Total Syntheses of Incarviditone and Incarvilleatone. Carreira, E. M; Breitler, S. Synfacts 2012, 8, 1287.
Highlighted on ORGANIC CHEMISTRY PORTAL: Total Synthesis of C-O Ring-Containing Natural Products. Lambert, T. H. Org. Chem. Highlights 2013, April 15.
Postdoctoral and Graduate Work
A Domino Diels–Alder Approach toward the Tetracyclic Nicandrenone Framework. Mackay, E. G.; Nörret, M.; Wong, L. S.-M.; Louis, I.; Lawrence, A. L.; Willis, A. C.; Sherburn, M. S.* Org. Lett. 2015, 17, 5517–5519.
Pseudopterosin synthesis from a chiral cross-conjugated hydrocarbon through a series of cycloadditions. Newton, C. G.; Drew, S. L.; Lawrence, A. L.; Willis, A. C.; Paddon-Row, M. N.;* Sherburn, M. S.* Nature Chem. 2015, 7, 82–86.
Domino Cycloaddition Organocascades of Dendralenes. Green, N. J.; Lawrence, A. L.; Bojase, G.; Willis, A. C.; Paddon-Row, M. N.;* Sherburn, M. S.* Angew. Chem. Int. Ed. 2013, 52, 8333–8336.
1,1-Divinylallene. Cergol, K. M.; Newton, C. G.; Lawrence, A. L.; Willis, A. C.; Paddon-Row, M. N.;* Sherburn, M. S.* Angew. Chem. Int. Ed. 2011, 50, 10425–10428.
A Short Biomimetic Synthesis of the Meroterpenoids Guajadial and Psidial A. Lawrence, A. L.; Adlington, R. M.; Baldwin, J. E.; Lee, V.;* Kershaw, J. A.; Thompson, A. L. Org. Lett. 2010, 12, 1676–1679.
Regioselective coupling reactions of 2,4-diaminopyridine derivatives with aryl halides: the synthesis of elaborated pyridines. Bio, M. M.;* Cleator, E.;* Davies, A. J.; Hamilton, S. E.; Lawrence, A. L.; Sheen, F. J.; Stewart, G. W.; Wilson, R. D. Tetrahedron 2009, 44, 8950–8955.
Studies towards the Synthesis of Coprinolone, Δ6-Coprinolone, and Radulone A via an Anionic Electrocyclization Cascade. Lawrence, A. L.; Adlington, R. M.;* Lee, V. Synlett 2008, 14, 2087–2088.
Investigations towards the synthesis of (−)-coprinolone, via a thermal 8π–6π electrocyclization cascade of 1,5,7-trien-4-ones. Lawrence, A. L.; Wegner, H. A.; Jacobsen, M. F.; Adlington, R. M.; Baldwin, J. E.* Tetrahedron Lett. 2006, 47, 8717–8720.
Trace Metal Detection in Sibenik Bay, Croatia: Cadmium, Lead and Copper with Anodic Stripping Voltammetry and Manganese via Sonoelectrochemistry. A Case Study. Lawrence, A. L.; Goodwin, A.; Banks, C. E.; Wantz, F.; Omanovic, D.; Komorsky-Lovric, S.; Compton, R. G.;* J. Iran. Chem. Soc. 2006, 3, 128–139.
On-site monitoring of trace levels of free manganese in sea water via sonoelectroanalysis using a boron-doped diamond electrode. Lawrence, A. L.; Goodwin, A.; Banks, C. E.; Wantz, F.; Omanovic, D.; Komorsky-Lovric, S.; Compton, R. G.;* Anal. Chim. Acta. 2005, 533, 141–145.